Article
Conditions of endoplasmic reticulum stress stimulate lipid droplet formation in Saccharomyces cerevisiae.
The Biochemical journal - 23 Oct 2009
Fei Weihua, Wang Han, Fu Xin, Bielby Christopher, Yang Hongyuan
Abstract excerpt
LDs (lipid droplets) are cellular organelles which can be found in nearly all eukaryotic cells. Despite their importance in cell biology, the mechanism underlying LD biogenesis remains largely unknown. In the present study we report that conditions of ER (endoplasmic reticulum) stress stimulate LD formation in Saccharomyces cerevisiae. We found that LDs accumulated in yeast mutants with compromised protein...
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