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Article

Phenotypic effects of membrane protein overexpression in Saccharomyces cerevisiae.

Proceedings of the National Academy of Sciences of the United States of America - 25 Jul 2006

Osterberg Marie, Kim Hyun, Warringer Jonas, Melén Karin, Blomberg Anders, von Heijne Gunnar

Abstract excerpt

Large-scale protein overexpression phenotype screens provide an important complement to the more common gene knockout screens. Here, we have targeted the so far poorly understood Saccharomyces cerevisiae membrane proteome and report growth phenotypes for a strain collection overexpressing approximately 600 C-terminally tagged integral membrane proteins grown both under normal and three different stress...

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Identifiers

PMID: 16847257
DOI: 10.1073/pnas.0604078103
PMCID: PMC1544056

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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