Article
An ancestry informative marker set for determining continental origin: validation and extension using human genome diversity panels.
BMC genetics - 24 Jul 2009
Nassir Rami, Kosoy Roman, Tian Chao, White Phoebe A, Butler Lesley M, Silva Gabriel, Kittles Rick, Alarcon-Riquelme Marta E, Gregersen Peter K, Belmont John W, De La Vega Francisco M, Seldin Michael F
Abstract excerpt
BACKGROUND: Case-control genetic studies of complex human diseases can be confounded by population stratification. This issue can be addressed using panels of ancestry informative markers (AIMs) that can provide substantial population substructure information. Previously, we described a panel of 128 SNP AIMs that were designed as a tool for ascertaining the origins of subjects from Europe, Sub-Saharan Africa,...
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