Article
Ancestry informative marker sets for determining continental origin and admixture proportions in common populations in America.
Human mutation - 1 Jan 2009
Kosoy Roman, Nassir Rami, Tian Chao, White Phoebe A, Butler Lesley M, Silva Gabriel, Kittles Rick, Alarcon-Riquelme Marta E, Gregersen Peter K, Belmont John W, De La Vega Francisco M, Seldin Michael F
Abstract excerpt
To provide a resource for assessing continental ancestry in a wide variety of genetic studies, we identified, validated, and characterized a set of 128 ancestry informative markers (AIMs). The markers were chosen for informativeness, genome-wide distribution, and genotype reproducibility on two platforms (TaqMan assays and Illumina arrays). We analyzed genotyping data from 825 subjects with diverse ancestry,...
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