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Article

Low pH-triggered beta-propeller switch of the low-density lipoprotein receptor assists rhinovirus infection.

Journal of virology - 1 Nov 2009

Konecsni Tuende, Berka Ursula, Pickl-Herk Angela, Bilek Gerhard, Khan Abdul Ghafoor, Gajdzig Leszek, Fuchs Renate, Blaas Dieter

Abstract excerpt

Minor group human rhinoviruses (HRVs) bind three members of the low-density lipoprotein receptor (LDLR) family: LDLR proper, very-LDLR (VLDLR) and LDLR-related protein (LRP). Whereas ICAM-1, the receptor of major group HRVs actively contributes to viral uncoating, LDLRs are rather considered passive vehicles for cargo delivery to the low-pH environment of endosomes. Since the Tyr-Trp-Thr-Asp beta-propeller domain...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19706701
DOI: 10.1128/JVI.01312-09
PMCID: PMC2772763

Genes

LDLR
VLDLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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