Article
Formation of rhinovirus-soluble ICAM-1 complexes and conformational changes in the virion.
Journal of virology - 1 Jan 1993
Hoover-Litty H, Greve J M
Abstract excerpt
Viral receptors serve both to target viruses to specific cell types and to actively promote the entry of bound virus into cells. Human rhinoviruses (HRVs) can form complexes in vitro with a truncated soluble form of the HRV cell surface receptor, ICAM-1. These complexes appear to be stoichiometric, with approximately 60 ICAM molecules bound per virion or 1 ICAM-1 molecule per icosahedral face of the capsid. The...
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