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Article

The Q motif of a viral packaging motor governs its force generation and communicates ATP recognition to DNA interaction.

Proceedings of the National Academy of Sciences of the United States of America - 25 Aug 2009

Tsay James M, Sippy Jean, Feiss Michael, Smith Douglas E

Abstract excerpt

A key step in the assembly of many viruses is the packaging of DNA into preformed procapsids by an ATP-powered molecular motor. To shed light on the motor mechanism we used single-molecule optical tweezers measurements to study the effect of mutations in the large terminase subunit in bacteriophage lambda on packaging motor dynamics. A mutation, K84A, in the putative ATPase domain driving DNA translocation was...

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Identifiers

PMID: 19706522
DOI: 10.1073/pnas.0904364106
PMCID: PMC2732826

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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