Article
Strong subunit coordination drives a powerful viral DNA packaging motor.
Proceedings of the National Academy of Sciences of the United States of America - 9 Apr 2013
Andrews Benjamin T, Catalano Carlos Enrique
Abstract excerpt
Terminase enzymes are viral motors that package DNA into a preformed capsid and are of interest both therapeutically and as potential nano-machines. The enzymes excise a single genome from a concatemeric precursor (genome maturation) and then package the duplex to near-crystalline density (genome packaging). The functional motors are oligomers of protomeric subunits and are the most powerful motors currently...
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