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Article

Compression of the DNA substrate by a viral packaging motor is supported by removal of intercalating dye during translocation.

Proceedings of the National Academy of Sciences of the United States of America - 11 Dec 2012

Dixit Aparna Banerjee, Ray Krishanu, Black Lindsay W

Abstract excerpt

Viral genome packaging into capsids is powered by high-force-generating motor proteins. In the presence of all packaging components, ATP-powered translocation in vitro expels all detectable tightly bound YOYO-1 dye from packaged short dsDNA substrates and removes all aminoacridine dye from packaged genomic DNA in vivo. In contrast, in the absence of packaging, the purified T4 packaging ATPase alone can only...

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Identifiers

PMID: 23185020
DOI: 10.1073/pnas.1214318109
PMCID: PMC3528532

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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