Article
Time course of insulin resistance during antiviral therapy in non-diabetic, non-cirrhotic patients with genotype 1 HCV infection.
Antiviral therapy - 1 Jan 2009
Petta Salvatore, Cammà Calogero, Di Marco Vito, Cabibi Daniela, Ciminnisi Stefania, Caldarella Rosalia, Licata Anna, Massenti Maria Fatima, Marchesini Giulio, Craxì Antonio
Abstract excerpt
BACKGROUND: Genotype 1 (G1) hepatitis C virus (HCV) is associated with insulin resistance (IR) and its clearance seems to improve insulin sensitivity. We aimed to evaluate the time course of IR in response to antiviral therapy in non-diabetic, non-cirrhotic G1 HCV patients and to assess the effect of metabolic factors on sustained virological response (SVR). METHODS: A total of 83 consecutive treatment-naive G1...
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