Article
Viral clearance is associated with improved insulin resistance in genotype 1 chronic hepatitis C but not genotype 2/3.
Gut - 1 Jan 2012
Thompson Alexander J, Patel Keyur, Chuang Wan-Long, Lawitz Eric J, Rodriguez-Torres Maribel, Rustgi Vinod K, Flisiak Robert, Pianko Stephen, Diago Moises, Arora Sanjeev, Foster Graham R, Torbenson Michael, Benhamou Yves, Nelson David R, Sulkowski Mark S, Zeuzem Stefan, Pulkstenis Erik, Subramanian G Mani, McHutchison John G
Abstract excerpt
OBJECTIVES: Genotype-specific associations between hepatitis C virus (HCV) and insulin resistance (IR) have been described, but a causal relationship remains unclear. This study investigated the association between a sustained virological response (SVR) and IR after chronic HCV therapy. METHODS: 2255 treatment-naive patients with chronic HCV genotype 1 or 2/3 were enrolled in two phase 3 trials of albinterferon...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
