Article
Insulin resistance predicts rapid virological response in non-diabetic, non-cirrhotic genotype 1 HCV patients treated with peginterferon alpha-2b plus ribavirin.
Journal of hepatology - 1 Dec 2009
Grasso Alessandro, Malfatti Federica, De Leo Pasqualina, Martines Hugo, Fabris Paolo, Toscanini Federica, Anselmo Marco, Menardo Giorgio
Abstract excerpt
BACKGROUND/AIMS: The rapid decline in hepatitis C virus RNA is crucial for determining the outcome of therapy in patients with genotype 1 chronic hepatitis C. However, the variables influencing the early phase of viral decay are still largely unexplored. We aimed to assess which pre-treatment variable may predict rapid virologic response (RVR) and sustained virologic response (SVR). METHODS: We evaluated 90...
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