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Article

Insulin resistance and diabetes increase fibrosis in the liver of patients with genotype 1 HCV infection.

The American journal of gastroenterology - 1 May 2008

Petta Salvatore, Cammà Calogero, Di Marco Vito, Alessi Nicola, Cabibi Daniela, Caldarella Rosalia, Licata Anna, Massenti Fatima, Tarantino Giuseppe, Marchesini Giulio, Craxì Antonio

Abstract excerpt

OBJECTIVES: Metabolic factors may affect the course of chronic hepatitis C (CHC). Insulin resistance (IR) determines steatosis, but its direct role in affecting progression of hepatic fibrosis is less clear. We aimed to assess whether increasing degrees of IR, up to overt diabetes, are linked to steatosis and higher stages of fibrosis in patients with CHC resulting from genotype 1 HCV (G1-HCV). METHODS: Two...

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PMID: 18477344
DOI: 10.1111/j.1572-0241.2008.01813.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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