Article
Insulin resistance impairs sustained response rate to peginterferon plus ribavirin in chronic hepatitis C patients.
Gastroenterology - 1 Mar 2005
Romero-Gómez Manuel, Del Mar Viloria Maria, Andrade Raúl J, Salmerón Javier, Diago Moisés, Fernández-Rodríguez Conrado M, Corpas Raquel, Cruz Marina, Grande Lourdes, Vázquez Luis, Muñoz-De-Rueda Paloma, López-Serrano Pilar, Gila Ana, Gutiérrez María L, Pérez Celia, Ruiz-Extremera Angela, Suárez Emilio, Castillo Jesús
Abstract excerpt
BACKGROUND & AIMS: We evaluated the effect of insulin resistance and viral factors on sustained virological response in patients with chronic hepatitis C treated with peginterferon plus ribavirin. METHODS: Patients (n=159; 94 men; age, 41.7 +/- 11.1 years) with chronic hepatitis C (genotype 1, n=113; non-1 genotype, n=46) received treatment with interferon plus ribavirin. Serum levels of leptin and insulin were...
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