Article
Comprehensive evaluation of Streptococcus sanguinis cell wall-anchored proteins in early infective endocarditis.
Infection and immunity - 1 Nov 2009
Turner Lauren Senty, Kanamoto Taisei, Unoki Takeshi, Munro Cindy L, Wu Hui, Kitten Todd
Abstract excerpt
Streptococcus sanguinis is a member of the viridans group of streptococci and a leading cause of the life-threatening endovascular disease infective endocarditis. Initial contact with the cardiac infection site is likely mediated by S. sanguinis surface proteins. In an attempt to identify the proteins required for this crucial step in pathogenesis, we searched for surface-exposed, cell wall-anchored proteins...
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