Article
Phenotypic characterization of Streptococcus sanguis virulence factors associated with bacterial endocarditis.
Infection and immunity - 1 Feb 1990
Herzberg M C, Gong K, MacFarlane G D, Erickson P R, Soberay A H, Krebsbach P H, Manjula G, Schilling K, Bowen W H
Abstract excerpt
Certain strains of Streptococcus sanguis adhere (Adh+) selectively to human platelets and, in plasma, induce them to aggregate (Agg+) into in vitro thrombi. In this study, we examined 18 recent endocarditis and dental plaque isolates of microorganisms that were biotyped as S. sanguis for coexpres...
Topics
- Animals
- Antibodies, Monoclonal
- Bacterial Adhesion
- Endocarditis, Bacterial
- Glucosyltransferases
- Hexosyltransferases
- Mice
- Mice, Inbred BALB C
- Phenotype
- Platelet Aggregation
- Streptococcus sanguis
- Virulence
