Article
Positive association between ALDH1A2 and schizophrenia in the Chinese population.
Progress in neuro-psychopharmacology & biological psychiatry - 13 Nov 2009
Wan Chunling, Shi Yongyong, Zhao Xinzhi, Tang Wei, Zhang Ming, Ji Baohu, Zhu Hui, Xu Yifeng, Li Huafang, Feng Guoyin, He Lin
Abstract excerpt
Vitamin A (retinol), in the biologically active form of retinoic acid (RA), has been proposed as involved in the pathogenesis of schizophrenia. We hypothesized that genetic basis of genes encoding RA metabolism enzymes, which control the cellular RA level, might be associated with this disease. This cascade genetic association model, using markers in genes of synthesis and degradation enzymes within the retinoid...
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