Article
Common variants conferring risk of schizophrenia: a pathway analysis of GWAS data.
Schizophrenia research - 1 Sept 2010
Jia Peilin, Wang Lily, Meltzer Herbert Y, Zhao Zhongming
Abstract excerpt
Unlike the typical analysis of single markers in genome-wide association studies (GWAS), we incorporated Gene Set Enrichment Analysis (GSEA) and hypergeometric test and combined them using Fisher's combined method to perform pathway-based analysis in order to detect genes' combined effects on mediating schizophrenia. A few pathways were consistently found to be top ranked and likely associated with schizophrenia...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
