Article
The interaction of ASAH1 and NGF gene involving in neurotrophin signaling pathway contributes to schizophrenia susceptibility and psychopathology.
Progress in neuro-psychopharmacology & biological psychiatry - 10 Jan 2021
Su Yousong, Yang Lu, Li Zezhi, Wang Weidi, Xing Mengjuan, Fang Yu, Cheng Ying, Lin Guan Ning, Cui Donghong
Abstract excerpt
The neurodevelopmental hypothesis of schizophrenia has been widely accepted. In light of our previous microarray data, two neurodevelopment-related genes were focused on inclduing the N-acylsphingosine amidohydrolase 1 gene (ASAH1) and the nerve growth factor gene (NGF). The evidence that ASAH1 and NGF are associated with schizophrenia is far from conclusive. Furthermore, their interactions in schizophrenia have...
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