Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Relationship between retinol metabolism and hepatocellular carcinoma: a comprehensive analysis of Mendelian randomization, prognostic characteristic and experiment

11 Apr 2025

Abstract excerpt

PURPOSE: Retinol metabolism is intricately linked to the occurrence and progression of hepatocellular carcinoma (HCC); however, the precise pathogenic relationship between them remains elusive. The aim of this study was to elucidate the characteristics of retinol metabolism in HCC through Mendelian randomization, prognostic model and experimental validation. METHODS: We used transcriptomic data related to HCC in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Lymphoblastic Leukemia research
Share to Ferroptosis and cancer prognosis
Share to Retinoids in leukemia and cellular processes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40210831
DOI: 10.1007/s12672-025-02295-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Relationship between retinol metabolism and hepatocellular carcinoma: a comprehensive analysis of Mendelian randomization, prognostic characteristic and experimentPMID 40210831Read ↗

The association between retinol metabolic activity and the risk of hepatocellular carcinoma: an analysis based on bulk RNA sequencing and mendelian randomizationSemantic proximity Read ↗

Mendelian randomization analysis identified serum palmitoylcarnitine as a biomarker for hepatocellular carcinomaSemantic proximity Read ↗

Construction of a lipid metabolism-related risk model for hepatocellular carcinoma by single cell and machine learning analysisSemantic proximity Read ↗

DNA methylation and gene expression profiling highlight retinol metabolism's vital role in Hepatocellular carcinoma developmentSemantic proximity Read ↗

Identification of novel targets associated with cholesterol metabolism in nonalcoholic fatty liver disease: a comprehensive study using Mendelian randomization combined with transcriptome analysisSemantic proximity Read ↗

Causal association of cholesterol metabolism-related proteins with hepatocellular carcinoma and dysfunction-associated steatotic liver disease: a mendelian randomization studySemantic proximity Read ↗

A Novel Nomogram Based on Lipid Metabolism-related Risk Gene Expression Can Better Predict Overall Survival for Hepatocellular CarcinomaSemantic proximity Read ↗

Comprehensive analysis of Mendelian randomization and single-cell sequencing reveals the causal relationship between intrahepatic cholangiocarcinoma and chronotype-related genesSemantic proximity Read ↗

Transcriptome analysis combined with Mendelian randomization screening for biomarkers causally associated with diabetic retinopathySemantic proximity Read ↗

Identification and validation of AKR1C1/2/3 as hepatocellular carcinoma risk modules via an integrated strategySemantic proximity Read ↗

Comprehensive analysis of the clinical and biological significances of cholesterol metabolism in lower-grade gliomasSemantic proximity Read ↗

Causal association between lipid-lowering drugs and cancers: A drug target Mendelian randomization study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.