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Article

Association of a single nucleotide polymorphism in the constitutive androstane receptor gene with bone mineral density.

Geriatrics & gerontology international - 1 Sept 2009

Urano Tomohiko, Usui Takahiko, Shiraki Masataka, Ouchi Yasuyoshi, Inoue Satoshi

Abstract excerpt

BACKGROUND: Nuclear receptors play an important role in bone metabolism. In bone cells, the vitamin D receptor (VDR) and the steroid and xenobiotic receptor (SXR) are activated by vitamin D and vitamin K2, respectively. VDR and SXR are the NR1I subfamily members of nuclear receptors. We speculated that the constitutive androstane receptor (CAR), the third member of the NR1I subfamily, also could be implicated in...

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Source

Identifiers

PMID: 19702932
DOI: 10.1111/j.1447-0594.2009.00527.x

Genes

VDR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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