Article
A1, Cw7, B8, DR3 HLA antigen combination associated with rapid decline of T-helper lymphocytes in HIV-1 infection. A report from the Multicenter AIDS Cohort Study.
Lancet (London, England) - 21 Apr 1990
Kaslow R A, Duquesnoy R, VanRaden M, Kingsley L, Marrari M, Friedman H, Su S, Saah A J, Detels R, Phair J
Abstract excerpt
108 seropositive homosexual men were examined for associations between HLA phenotype and progression of human immunodeficiency virus type 1 (HIV-1) infection. Among men of predominantly European ethnic origin, 49 with very rapid 2-year declines in CD4+ lymphocyte counts showed significant differe...
Topics
- Acquired Immunodeficiency Syndrome
- CD4 Antigens
- Cohort Studies
- Evaluation Studies as Topic
- Genetic Linkage
- HIV-1
- HLA-A1 Antigen
- HLA-B8 Antigen
- HLA-C Antigens
- HLA-DR3 Antigen
- Haplotypes
- Histocompatibility Testing
- Homosexuality
- Humans