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Article

Shades of gray: a comparison of linkage disequilibrium between Hutterites and Europeans.

Genetic epidemiology - 1 Feb 2010

Thompson Emma E, Sun Ying, Nicolae Dan, Ober Carole

Abstract excerpt

Founder or isolated populations have advantages for genetic studies due to decreased genetic and environmental heterogeneity. However, whereas longer-range linkage disequilibrium (LD) in these populations is expected to facilitate gene localization, extensive LD may actually limit the ability for gene discovery. The North American Hutterite population is one of the best characterized young founder populations and...

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PMID: 19697328
DOI: 10.1002/gepi.20442
PMCID: PMC4238926

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