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Article

Are common disease susceptibility alleles the same in outbred and founder populations?

European journal of human genetics : EJHG - 1 Jul 2004

Newman Dina L, Hoffjan Sabine, Bourgain Catherine, Abney Mark, Nicolae Raluca I, Profits Elle T, Grow Michael A, Walker Karen, Steiner Lori, Parry Rodney, Reynolds Rebecca, McPeek Mary Sara, Cheng Suzanne, Ober Carole

Abstract excerpt

Founder populations have been the subjects of complex disease studies because of their decreased genetic heterogeneity, increased linkage disequilibrium and more homogeneous environmental exposures. However, it is possible that disease alleles identified in founder populations may not contribute...

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PMID: 15100713
DOI: 10.1038/sj.ejhg.5201191

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15100713-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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