Article
Bronchial epithelial cells cultured from clinically stable lung allograft patients promote the development of macrophages from monocytes rather than dendritic cells.
Thorax - 1 May 2009
Ward C, Eger K, Diboll J, Jones D, Haniffa M A, Brodlie M, Fisher A, Lordan J L, Corris P A, Hilkens C M U
Abstract excerpt
BACKGROUND: It is understood that chronic allograft failure occurs as a result of alloimmune and non-alloimmune injury. Dendritic cells (DC) are thought to be crucial in regulating (allo)immune airway damage and interactions with epithelial cells are likely. Studies in human lung transplantation are limited, however, and the available literature on DC is inconsistent. This study focused on the ex vivo influence...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.