Analysis of 3p allelic loss in papillary and nonpapillary renal cell carcinomas. Correlation with tumor karyotypes.

doi:10.1016/0165-4608(95)00274-x

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Article

Analysis of 3p allelic loss in papillary and nonpapillary renal cell carcinomas. Correlation with tumor karyotypes.

Cancer genetics and cytogenetics - 1 Apr 1996

Hughson M D, Meloni A, Dougherty S, Silva F G, Sandberg A A

Abstract excerpt

Nonpapillary renal cell carcinomas (RCCs) are characterized by deletions of the short arm of chromosome 3 (3p) and papillary RCCs by increased numbers of selected chromosomes. Although recent molecular genetic studies have reported some papillary RCCs to show loss of heterozygosity (LOH) on 3p, a...

Topics

Alleles
Carcinoma, Renal Cell
Chromosome Deletion
Chromosomes, Human, Pair 3
DNA, Satellite
Humans
Karyotyping
Kidney Neoplasms
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length

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