Article
No association of the TLR2 gene Arg753Gln polymorphism with rheumatic heart disease and Behçet's disease.
Clinical rheumatology - 1 Dec 2009
Coşan Fulya, Oku Başar, Cakiris Aris, Duymaz-Tozkir Julide, Mercanoğlu Fehmi, Saruhan-Direskeneli Güher, Ustek Duran, Gül Ahmet
Abstract excerpt
Behçet's disease (BD) is a multisystem inflammatory disorder of unknown etiology, and infections with different microorganisms including streptococci have been claimed as triggers of inflammatory attacks in BD pathogenesis. Toll-like receptor 2 (TLR2) has been known to recognize several microbial antigens including that of streptococci, and TLR2 gene Arg753Gln polymorphism has been reported to be strongly...
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