Article
Lack of association of Toll-like receptor 9 gene polymorphism with Behçet's disease in Japanese patients.
Tissue antigens - 1 Nov 2007
Ito A, Ota M, Katsuyama Y, Inoko H, Ohno S, Mizuki N
Abstract excerpt
Toll-like receptors (TLRs) play an important role in the induction of defense mechanisms of the innate and adaptive immune responses to microbial pathogens. Genetic polymorphisms within the TLR9 gene have been reported to be associated with a variety of inflammatory and infectious diseases. Behçet's disease (BD) is a chronic inflammatory disease, and the etiology of BD has yet to be fully elucidated. We...
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