Article
Genetic variants in XRCC2: new insights into colorectal cancer tumorigenesis.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Sept 2009
Curtin Karen, Lin Wei-Yu, George Rina, Katory Mark, Shorto Jennifer, Cannon-Albright Lisa A, Smith Gillian, Bishop D Timothy, Cox Angela, Camp Nicola J
Abstract excerpt
Polymorphisms in DNA double-strand break repair gene XRCC2 may play an important role in colorectal cancer etiology, specifically in disease subtypes. Associations of XRCC2 variants and colorectal cancer were investigated by tumor site and tumor instability status in a four-center collaboration including three U.K. case-control studies (Sheffield, Leeds, and Dundee) and a U.S. case-control study of cases from...
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