Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

New insights on familial colorectal cancer type X syndrome.

Scientific reports - 18 Feb 2022

Garcia Felipe Antonio de Oliveira, de Andrade Edilene Santos, de Campos Reis Galvão Henrique, da Silva Sábato Cristina, Campacci Natália, de Paula Andre Escremin, Evangelista Adriane Feijó, Santana Iara Viana Vidigal, Melendez Matias Eliseo, Reis Rui Manuel, Palmero Edenir Inez

Abstract excerpt

Familial colorectal cancer type X (FCCTX) is a heterogeneous colorectal cancer predisposition syndrome that, although displays a cancer pattern similar to Lynch syndrome, is mismatch repair proficient and does not exhibit microsatellite instability. Besides, its genetic etiology remains to be elucidated. In this study we performed germline exome sequencing of 39 cancer-affected patients from 34 families at risk...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ataxia Telangiectasia Mutated Proteins
Share to Checkpoint Kinase 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Glycosylases

Share to DNA Mismatch Repair

Share to Endodeoxyribonucleases

Share to Exodeoxyribonucleases

Share to Multifunctional Enzymes

Share to Recombinases

Source

Open in PubMed Open full text

Identifiers

PMID: 35181726
DOI: 10.1038/s41598-022-06782-8
PMCID: PMC8857274

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

New insights on familial colorectal cancer type X syndrome.PMID 35181726Read ↗

Familial Colorectal Cancer Type X (FCCTX) and the correlation with various genes-A systematic review.Semantic proximity Read ↗

Familial colorectal cancer type X: genetic profiles and phenotypic features.Semantic proximity Read ↗

Updates in the field of hereditary nonpolyposis colorectal cancer.Semantic proximity Read ↗

Whole-exome sequencing identifies rare pathogenic variants in new predisposition genes for familial colorectal cancer.Semantic proximity Read ↗

Gene discovery in familial cancer syndromes by exome sequencing: prospects for the elucidation of familial colorectal cancer type X.Semantic proximity Read ↗

Detection of germline variants with pathogenic potential in 48 patients with familial colorectal cancer by using whole exome sequencing.Semantic proximity Read ↗

Search for germline gene variants in colorectal cancer families presenting with multiple primary colorectal cancers.Semantic proximity Read ↗

Broadening Risk Profile in Familial Colorectal Cancer Type X; increased risk for five cancer types in the national Danish cohortSemantic proximity Read ↗

The Fanconi anemia DNA damage repair pathway in the spotlight for germline predisposition to colorectal cancer.Semantic proximity Read ↗

Comprehensive profiling of 1015 patients’ exomes reveals genomic-clinical associations in colorectal cancerSemantic proximity Read ↗

Germline and Somatic Whole-Exome Sequencing Identifies New Candidate Genes Involved in Familial Predisposition to Serrated Polyposis SyndromeSemantic proximity Read ↗

Distinct Gene Expression Signatures in Lynch Syndrome and Familial Colorectal Cancer Type XSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.