Article
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.
Gastroenterology - 1 Apr 2013
Peters Ulrike, Jiao Shuo, Schumacher Fredrick R, Hutter Carolyn M, Aragaki Aaron K, Baron John A, Berndt Sonja I, Bézieau Stéphane, Brenner Hermann, Butterbach Katja, Caan Bette J, Campbell Peter T, Carlson Christopher S, Casey Graham, Chan Andrew T, Chang-Claude Jenny, Chanock Stephen J, Chen Lin S, Coetzee Gerhard A, Coetzee Simon G, Conti David V, Curtis Keith R, Duggan David, Edwards Todd, Fuchs Charles S, Gallinger Steven, Giovannucci Edward L, Gogarten Stephanie M, Gruber Stephen B, Haile Robert W, Harrison Tabitha A, Hayes Richard B, Henderson Brian E, Hoffmeister Michael, Hopper John L, Hudson Thomas J, Hunter David J, Jackson Rebecca D, Jee Sun Ha, Jenkins Mark A, Jia Wei-Hua, Kolonel Laurence N, Kooperberg Charles, Küry Sébastien, Lacroix Andrea Z, Laurie Cathy C, Laurie Cecelia A, Le Marchand Loic, Lemire Mathieu, Levine David, Lindor Noralane M, Liu Yan, Ma Jing, Makar Karen W, Matsuo Keitaro, Newcomb Polly A, Potter John D, Prentice Ross L, Qu Conghui, Rohan Thomas, Rosse Stephanie A, Schoen Robert E, Seminara Daniela, Shrubsole Martha, Shu Xiao-Ou, Slattery Martha L, Taverna Darin, Thibodeau Stephen N, Ulrich Cornelia M, White Emily, Xiang Yongbing, Zanke Brent W, Zeng Yi-Xin, Zhang Ben, Zheng Wei, Hsu Li
Abstract excerpt
BACKGROUND & AIMS: Heritable factors contribute to the development of colorectal cancer. Identifying the genetic loci associated with colorectal tumor formation could elucidate the mechanisms of pathogenesis. METHODS: We conducted a genome-wide association study that included 14 studies, 12,696 cases of colorectal tumors (11,870 cancer, 826 adenoma), and 15,113 controls of European descent. The 10 most...
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