Article
TGFBR1 haplotypes and risk of non-small-cell lung cancer.
Cancer research - 1 Sept 2009
Lei Zhe, Liu Reng-Yun, Zhao Jun, Liu Zeyi, Jiang Xiefang, You Weiming, Chen Xiao-Feng, Liu Xia, Zhang Kui, Pasche Boris, Zhang Hong-Tao
Abstract excerpt
Transforming growth factor beta (TGF-beta) receptors are centrally involved in TGF-beta-mediated cell growth and differentiation and are frequently inactivated in non-small-cell lung cancer (NSCLC). Constitutively decreased type I TGF-beta receptor (TGFBR1) expression is emerging as a novel tumor...
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