Article
Single nucleotide polymorphisms of the TGFB1 gene and lung cancer risk in a Korean population.
Cancer genetics and cytogenetics - 1 Aug 2006
Park Kyong Hwa, Lo Han Sle Gi, Whang Young Mi, Lee Hyo Jung, Yoo Young Do, Lee Jae Won, Shin Sang Won, Kim Yeul Hong
Abstract excerpt
The present study was conducted to investigate the association between single nucleotide polymorphisms (SNPs) of the transforming growth factor-beta 1 (TGFB1) gene and susceptibility to lung cancer and the clinical effect of the SNPs on lung cancer progression in a Korean population. Two polymorphisms in the promoter region of the TGFB1 (T-1572C, C-509T), and one SNP in codon 10 (T+869C) were determined using a...
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