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Article

Association of PARP1-specific polymorphisms and haplotypes with non-small cell lung cancer subtypes.

PloS one - 1 Jan 2020

Jin Jing, Robeson Heather, Fagan Pebbles, Orloff Mohammed S

Abstract excerpt

OBJECTIVE: The carcinogenesis role of PARP1 in lung cancer is still not clear. Analysis at allelic levels cannot fully explain the function of PARP1 on lung cancer. Our study aims to further explore the relation between PARP1 haplotypes and lung cancer. MATERIALS AND METHODS: DNA and RNA were extracted from non-small cell lung cancer (NSCLC) tumor and adjacent normal fresh frozen tissue. Five PARP1-SNPs were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33284833
DOI: 10.1371/journal.pone.0243509
PMCID: PMC7721167

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