Article
Role of phosphocholine cytidylyltransferase alpha in lung development.
Molecular and cellular biology - 1 Feb 2007
Tian Yong, Zhou Ruobing, Rehg Jerold E, Jackowski Suzanne
Abstract excerpt
Lung development depends upon the differentiation and expansion of a variety of specialized epithelial cell types, including distal type I and type II pneumocytes in the late term. Previous studies have shown a strict dependence on the choline cytidylyltransferase alpha isoform (CCTalpha) to mediate membrane phospholipid formation in cultured cells and during preimplantation embryogenesis. CCTalpha expression is...
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