Article
Membrane binding modulates the quaternary structure of CTP:phosphocholine cytidylyltransferase.
The Journal of biological chemistry - 2 Jul 2004
Xie Mingtang, Smith Jillian L, Ding Ziwei, Zhang Daqing, Cornell Rosemary B
Abstract excerpt
CTP:phosphocholine cytidylyltransferase (CCT), a key enzyme that controls phosphatidylcholine synthesis, is regulated by reversible interactions with membranes containing anionic lipids. Previous work demonstrated that CCT is a homodimer. In this work we show that the structure of the dimer inter...
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