Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lack of association of NKX2-3, IRGM, and ATG16L1 inflammatory bowel disease susceptibility variants with celiac disease.

Human immunology - 1 Nov 2009

Dema Bárbara, Fernández-Arquero Miguel, Maluenda Carlos, Polanco Isabel, Figueredo M Angeles, de la Concha Emilio G, Urcelay Elena, Núñez Concepción

Abstract excerpt

Evidence about the presence of susceptibility factors shared among different autoimmune diseases is increasing. Based on this idea, NKX2-3, ATG16L1, and IRGM which are well-established inflammatory bowel disease risk factors, could be new celiac disease (CD) candidate genes. NKX2-3 encodes a transcription factor that in mice seems to be involved in gut development. The ATG16L1 and IRGM genes act in autophagy, a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy-Related Proteins
Share to Carrier Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Celiac Disease

Share to GTP-Binding Proteins

Share to Homeodomain Proteins

Share to Inflammatory Bowel Diseases

Share to Polymorphism, Single Nucleotide

Share to Transcription Factors

Source

Identifiers

PMID: 19683022
DOI: 10.1016/j.humimm.2009.08.004

Genes

IRGM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lack of association of NKX2-3, IRGM, and ATG16L1 inflammatory bowel disease susceptibility variants with celiac disease.PMID 19683022Read ↗

Autophagy gene ATG16L1 but not IRGM is associated with Crohn's disease in Canadian children.Semantic proximity Read ↗

IRGM variants and susceptibility to inflammatory bowel disease in the German population.Semantic proximity Read ↗

Associations between NOD2, IRGM and ORMDL3 polymorphisms and pediatric-onset inflammatory bowel disease in the Lithuanian population.Semantic proximity Read ↗

Autoimmune disease association signals in CIITA and KIAA0350 are not involved in celiac disease susceptibility.Semantic proximity Read ↗

Positive association of genetic variants in the upstream region of NKX2-3 with Crohn's disease in Japanese patients.Semantic proximity Read ↗

NKX2-3 and IRGM variants are associated with disease susceptibility to IBD in Eastern European patients.Semantic proximity Read ↗

Lack of association of the 3'-UTR polymorphism in the NFKBIA gene with Crohn's disease in an Israeli cohort.Semantic proximity Read ↗

Autophagy 16-like 1 rs2241880 G allele is associated with Crohn's disease in German children.Semantic proximity Read ↗

Classification of genetic profiles of Crohn's disease: a focus on the ATG16L1 gene.Semantic proximity Read ↗

The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population.Semantic proximity Read ↗

Genetics of inflammatory bowel disease in Asia: systematic review and meta-analysis.Semantic proximity Read ↗

Lack of evidence for association of primary sclerosing cholangitis and primary biliary cirrhosis with risk alleles for Crohn's disease in Polish patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.