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Article

NKX2-3 and IRGM variants are associated with disease susceptibility to IBD in Eastern European patients.

World journal of gastroenterology - 7 Nov 2010

Meggyesi Nora, Kiss Lajos S, Koszarska Magdalena, Bortlik Martin, Duricova Dana, Lakatos Laszlo, Molnar Tamas, Leniček Martin, Vítek Libor, Altorjay Istvan, Papp Maria, Tulassay Zsolt, Miheller Pal, Papp Janos, Tordai Attila, Andrikovics Hajnalka, Lukas Milan, Lakatos Peter Laszlo

Abstract excerpt

AIM: To investigate variants of immunity-related GTPase family M (IRGM) and NKX2-3 genes and genotype-phenotype in Eastern European patients with inflammatory bowel disease (IBD). METHODS: We analyzed 1707 Hungarian and Czech subjects with Crohn's disease (CD) (n = 810, age: 37.1 ± 12.6 years, du...

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Source

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Identifiers

PMID: 21049557
DOI: 10.3748/wjg.v16.i41.5233
PMCID: PMC2975094

Genes

IRGM
ECM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21049557-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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