Article
Genetic polymorphisms of interleukin-6 modulate fibrosis progression in mild chronic hepatitis C.
Human immunology - 1 Oct 2010
Falleti Edmondo, Fabris Carlo, Vandelli Carmen, Colletta Cosimo, Cussigh Annarosa, Smirne Carlo, Fontanini Elisabetta, Cmet Sara, Minisini Rosalba, Bitetto Davide, Toniutto Pierluigi, Pirisi Mario
Abstract excerpt
Genetic polymorphisms of interleukin-6 (IL-6) (-1363G>T, -597G>A, -572G>C, -174G>C, +2954G>C) may affect the outcomes of several diseases. This study was aimed to verify the role of these polymorphisms on the disease progression of patients with hepatitis C virus (HCV) infection and persistently normal transaminases (PNALT). A total of 121 PNALT patients did not receive any antiviral treatment but underwent...
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