Article
Disease progression in chronic hepatitis C: modifiable and nonmodifiable factors.
Gastroenterology - 1 May 2008
Missiha Sharif B, Ostrowski Mario, Heathcote E Jenny
Abstract excerpt
The hepatic complications of chronic hepatitis C (CHC) usually occur only after progression to cirrhosis has taken place. Progression to cirrhosis, however, is extremely variable and depends on a broad set of host and viral factors that modify the rate at which fibrosis develops in a given individual. Despite their inherent limitations, studies of the natural history of CHC have identified several nonmodifiable...
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