Article
fMRI activation during response inhibition and error processing: the role of the DAT1 gene in typically developing adolescents and those diagnosed with ADHD.
Neuropsychologia - 1 Jun 2011
Braet Wouter, Johnson Katherine A, Tobin Claire T, Acheson Ruth, McDonnell Caroline, Hawi Ziarah, Barry Edwina, Mulligan Aisling, Gill Michael, Bellgrove Mark A, Robertson Ian H, Garavan Hugh
Abstract excerpt
The DAT1 gene codes for the dopamine transporter, which clears dopamine from the synaptic cleft, and a variant of this gene has previously been associated with compromised response inhibition in both healthy and clinical populations. This variant has also been associated with ADHD, a disorder that is characterised by disturbed dopamine function as well as problems with response inhibition. In the present study we...
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