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Article

Scorpion primer PCR analysis for genotyping of allele variants of thiopurine s‑methyltransferase*3.

Molecular medicine reports - 1 Sept 2020

Yao Pu, Qu Xue-Mei, Ren Sai, Ren Xiao-Dong, Su Ning, Zhao Na, Wang Liu, Cheng Lin, Weng Bang-Bi, Sun Feng-Jun, Huang Qing

Abstract excerpt

Thiopurine S-methyltransferase (TPMT) plays an important role in the metabolism of thiopurines. Mutations in the TPMT gene can affect drug activity, which may have adverse effects in humans. Thus, genotyping can help elucidate genetic determinants of drug response to thiopurines and optimize the selection of drug therapies for individual patients, effectively avoiding palindromia during maintenance treatment...

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Identifiers

PMID: 32705177
DOI: 10.3892/mmr.2020.11283
PMCID: PMC7411393

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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