Article
Best1 is a gene regulated by nerve injury and required for Ca2+-activated Cl- current expression in axotomized sensory neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 12 Aug 2009
Boudes Mathieu, Sar Chamroeun, Menigoz Aurélie, Hilaire Cécile, Péquignot Marie O, Kozlenkov Alexei, Marmorstein Alan, Carroll Patrick, Valmier Jean, Scamps Frédérique
Abstract excerpt
We investigated the molecular determinants of Ca(2+)-activated chloride current (CaCC) expressed in adult sensory neurons after a nerve injury. Dorsal root ganglia express the transcripts of three gene families known to induce CaCCs in heterologous systems: bestrophin, tweety, and TMEM16. We foun...
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