Article
The T-lymphocyte response against myelin-associated glycoprotein and myelin basic protein in patients with multiple sclerosis.
Neurology - 1 Feb 1993
Zhang Y, Burger D, Saruhan G, Jeannet M, Steck A J
Abstract excerpt
In addition to myelin basic protein (MBP), other minor components of myelin, such as myelin-associated glycoprotein (MAG), may be important autoantigens in MS. To determine whether MAG might be involved in an autoimmune reaction in MS, we screened peripheral blood lymphocytes from MS patients and normal subjects for their sensitization to human MBP and MAG antigen using a [3H]thymidine incorporation assay. We...
Topics
- Adult
- Female
- HLA-D Antigens
- Humans
- Lymphocyte Activation
- Male
- Middle Aged
- Multiple Sclerosis
- Myelin Basic Protein
- Myelin Proteins
- Myelin-Associated Glycoprotein