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Article

Unaltered regulatory B-cell frequency and function in patients with multiple sclerosis.

Clinical immunology (Orlando, Fla.) - 1 Dec 2014

Michel Laure, Chesneau Melanie, Manceau Philippe, Genty Athenais, Garcia Alexandra, Salou Marion, Elong Ngono Annie, Pallier Annaïck, Jacq-Foucher Marylène, Lefrère Fabienne, Wiertlewski Sandrine, Soulillou Jean-Paul, Degauque Nicolas, Laplaud David-Axel, Brouard Sophie

Abstract excerpt

Multiple sclerosis (MS) is a chronic disease of the central nervous system (CNS) typically characterized by the recruitment of T cells into the CNS. However, certain subsets of B cells have been shown to negatively regulate autoimmune diseases and some data support a prominent role for B cells in MS physiopathology. For B cells in MS patients we analyzed subset frequency, cytokine secretion ability and...

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Identifiers

PMID: 25267439
DOI: 10.1016/j.clim.2014.09.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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