Article
Update on genetic predisposition to breast cancer.
Expert review of anticancer therapy - 1 Aug 2009
Ahmed Munaza, Lalloo Fiona, Evans D Gareth
Abstract excerpt
It has been evident for some time that individuals from some families exhibit a genetic predisposition to breast cancer. Since the discovery of the first breast cancer susceptibility gene, BRCA1 in the 1990s, much work has been carried out to identify further breast cancer susceptibility genes. This has led to the identification of another high-penetrance gene, BRCA2, a number of moderate-penetrance genes and,...
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