Article
Hereditary breast cancer.
Annual review of medicine - 1 Jan 1998
Ellisen L W, Haber D A
Abstract excerpt
Genetic predisposition is responsible for 5-10% of all breast cancer, and a much larger percent of early-onset disease. Within the past few years, a number of genes associated with a high risk of breast cancer have been identified, including BRCA1, BRCA2, p53, and the Cowden disease gene PTEN/MMA...
Topics
- Adult
- BRCA2 Protein
- Breast Neoplasms
- Disease Susceptibility
- Female
- Genes, BRCA1
- Genes, Tumor Suppressor
- Genes, p53
- Genetic Markers
- Genetic Predisposition to Disease
- Genetic Testing
- Germ-Line Mutation
- Hamartoma Syndrome, Multiple
- Heterozygote
- Humans
- Molecular Biology
- Mutation
- Neoplasm Proteins