Article
Genetic predisposition syndromes and their management.
The Surgical clinics of North America - 1 Apr 2013
Euhus David M, Robinson Linda
Abstract excerpt
Apart from BRCA1, BRCA2, and TP53, more than a dozen breast cancer susceptibility genes have been identified. Recognizing affected individuals depends on evaluation of cancer family history and recognition of certain phenotypic markers on physical examination. Genetic testing provides a powerful tool for individualized risk stratification. Mutation carriers have several options for managing risk, including...
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