Article
Considerations in genetic counseling for inherited breast cancer predisposition.
Seminars in radiation oncology - 1 Oct 2002
Robson Mark E, Offit Kenneth
Abstract excerpt
Of the 190000 women estimated to have been diagnosed with breast cancer in 2001, between 5% and 10% of them are likely to have developed their disease as the result of an inherited susceptibility. Although breast cancer is a component tumor of several familial cancer predisposition syndromes, mutations in BRCA1 and BRCA2 are the most commonly identified germline changes. Recognition of hereditary breast cancer is...
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