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Article

High-resolution HLA genotyping and severe cutaneous adverse reactions in lamotrigine-treated patients.

Pharmacogenetics and genomics - 1 Sept 2009

Kazeem Gbenga R, Cox Charles, Aponte Jennifer, Messenheimer John, Brazell Celia, Nelsen Andrew C, Nelson Matthew R, Foot Elizabeth

Abstract excerpt

BACKGROUND: Severe cutaneous adverse reactions (SCARs) are associated with over 200 medicines including lamotrigine, an antiepileptic drug. Previous studies have suggested the involvement of immune mechanisms in the development of drug-induced SCARs. METHODS: High-resolution HLA genotyping was pe...

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Identifiers

PMID: 19668019
DOI: 10.1097/FPC.0b013e32832c347d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19668019-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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